Severe Vitamin D Deficiency is Associated with
Increased Expression of Inflammatory
Cytokines in Painful Diabetic
Peripheral Neuropathy

Prevalansi Diabetes Melitus adalah 12,8 %, sekitar 60-70% mengalami neuropati dan setengahnya  berupa Diabetic, sedangkan pada  Peripheral Neuropathy (DPN) 25% mengalami painful Diabetic Peripheral Nueropathy . Tujuan studi adalah mengevaluasi hubungan vitamin D, hs-CRP, sitokin ( IL2, IL4, IL6, IL10 dan TNF-α.)

Defisiensi vitamin D yang berat berperan penting dalam patogenesis painful diabetic peripheral neuropathy melalui peningkatan kadar sitokin pro-inflamatori IL-6 dan TNF-α.

Jurnal Reading : Effect of Treating Acute Optic Neuritis With Bioequivalent Oral vs Intravenous Corticosteroids

Residen : dr. Aurelia Vania

Pembimbing : Dr.dr. I Putu Eka Widyadharma, M.Sc,  Sp.S (K)

 

Written by 

Leave a Reply

Your email address will not be published. Required fields are marked *